Devyser LynchFAP

Confidently localize variants in all exons of PMS2 with Devyser LynchFAP, a next-generation sequencing library prep kit that enables the analysis of the most relevant genes associated with Lynch syndrome, Familial Adenomatous Polyposis (FAP), and MUTYH-associated polyposis (MAP).

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Download the whitepaper: Detecting technically challenging PMS2 variants with NGS: Current techniques and future perspectives

Watch our on-demand webinar and learn more about Devyser LynchFAP

Detect mutations in 10 genes associated with hereditary cancer syndromes

Simple workflow

PMS2-specific solution for all PMS2 exons

Dedicated software

Product information

Targeted approach

Devyser LynchFAP enables analysis of sequence variants (SNVs, CNVs and indels) in 10 selected genes implicated in Lynch syndrome, Familial Adenomatous Polyposis (FAP), and MUTYH-Associated Polyposis (MAP) in genomic DNA isolated from blood. The simple workflow and ready-to-use reagents allow for laboratory efficiency. Genes included: MLH1, MSH2, MSH6, PMS2, EPCAM, APC, MUTYH, POLE, POLD1, and CTNNB1.

PMS2-specific solution

First commercial kit to include a long-range PCR to unambiguously determine variants in all PMS2 exons. By including a long-range PCR into the simplified workflow, it allows to confidently localize variants in all PMS2 exons – including those challenging regions that are homologous to its pseudogene PMS2CL.

Unravel complex genetics

With a dedicated software, evaluate PMS2 gene conversion and unravel complex genetic questions in a fast and intuitive way.

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the company embarked on a journey into the realm of Genomics. Since then, it has continuously evolved, presenting forward-looking and ingenious solutions in this field.

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