Automated screening and identification with single antigens
HISTO SPOT® HLA Antibody Analysis
Automated HLA Antibody Diagnostics using Single Antigens
HLA ANTIBODY DIAGNOSTICS – HISTO SPOT® HLA AB
HISTO SPOT® HLA AB is your system for pre- and post-transplantation. Because the detection of HLA antibodies is required in the preparation and follow-up of solid organ transplantation. It consists of the test kits, the MR.SPOT® Processor and the HLA AB module of the HISTO MATCH interpretation software. Thanks to the combination of these components, you will experience a high level of automation and a simplified workflow. Using a microarray assay with recombinant allele-specific proteins provides high-resolution results.
- Convenient: fully automated workflow without manual intervention
- Efficient: microarray assay with minimal sample volume (2-10 µl serum)
- Precise: direct identification of HLA antibodies, thanks to recombinant single antigens for HLA class I and HLA class II.
- Flexible: sample throughput of 1-96 samples
| Product | REF | Package |
| ® HISTO SPOT HLA AB ID Class I | 728100 | 48 tests |
| ® HISTO SPOT HLA AB ID Class II | 728101 | 48 tests |
| ® HISTO SPOT HLA AB Screen/ ID Class I | 728102 | 480 tests |
| ® HISTO SPOT HLA AB Screen/ ID Class II | 728103 | 480 tests |
| ® HISTO SPOT AB Reagent Kit | 728098 | 96 tests |
HLA antibody diagnostics: SeraScreen FCT microtest plates with deep frozen HLA-ABC typed lymphocytes
The microlymphocyte toxicity test (MLCT) is a procedure which has been used for many years in HLA antibody diagnostics. Herein, anti-HLA antibodies from the patient’s serum (if available) react with the corresponding membrane bound antigens of the human lymphocytes which are fixed on the microtest plate.
Determining HLA antibodies is required in the preparation and progress monitoring of solid organ transplants. HLA class I antibodies can also influence the progression of thrombocyte transfusions.
Our SeraScreen microtest plates contain ready to use pre-dripped peripheral lymphocytes from various donors to detect HLA antibodies. The plates are supplied with rabbit complement.
| Product | Description | Package | REF |
| SeraScreen FCT 60 | (incl. rabbit complement) | 5 plates à 1 Tests | 7250 |
| SeraScreen FCT 30 | (incl. rabbit complement) | 5 plates à 2 Tests | 7251 |